Q&A

How do phages attach to bacteria?

How do phages attach to bacteria?

To infect bacteria, most bacteriophages employ a ‘tail’ that stabs and pierces the bacterium’s membrane to allow the virus’s genetic material to pass through. The most sophisticated tails consist of a contractile sheath surrounding a tube akin to a stretched coil spring at the nanoscale.

What part of the bacteriophage attaches and anchors itself to the bacteria?

tail
Attachment: Proteins in the “tail” of the phage bind to a specific receptor (in this case, a sugar transporter) on the surface of the bacterial cell. Entry: The phage injects its double-stranded DNA genome into the cytoplasm of the bacterium.

How does transformation differ from Transduction and conjugation?

In transformation, a bacterium takes up a piece of DNA floating in its environment. In transduction, DNA is accidentally moved from one bacterium to another by a virus. In conjugation, DNA is transferred between bacteria through a tube between cells.

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How do bacteriophages infect different host cells?

A bacteriophage attaches itself to a susceptible bacterium and infects the host cell. Following infection, the bacteriophage hijacks the bacterium’s cellular machinery to prevent it from producing bacterial components and instead forces the cell to produce viral components.

How do bacteriophages recognize bacterial cells?

The phage possesses a genome of linear ds DNA contained within an icosahedral head. The tail consists of a hollow core through which the DNA is injected into the host cell. The tail fibers are involved with recognition of specific viral “receptors” on the bacterial cell surface.

What part of the bacteriophage gets injected into a bacterial cell?

Which part of the bacteriophage was injected into the bacterial cell? The bacteriophage injects its double-stranded Deoxyribonucleic Acid (DNA) genome into the cytoplasm of the bacterial cell. Notably, the tail contains a hollow core through which the injection of DNA takes place into the host cell.

Why can’t bacteriophages infect human cells?

Bacteriophages are viruses infecting bacterial cells. Since there is a lack of specific receptors for bacteriophages on eukaryotic cells, these viruses were for a long time considered to be neutral to animals and humans.

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Why do recipient cells become donor cells after conjugation?

Why do recipient cells become donor cells after conjugation has occurred? They are now genetically identical to the cell with which they conjugated. They have received proteins that allow them to produce a sex pilus. After conjugation, they retain the sex pilus that the donor cell use to form the attachment.

Why does a bacteriophage infect only specific species of bacteria?

To enter a host cell, bacteriophages attach to specific receptors on the surface of bacteria. This specificity means a bacteriophage can infect only certain bacteria bearing receptors to which they can bind, which in turn determines the phage’s host range.

What part of the bacteriophage actually enters the host cell?

The nucleic acid of bacteriophages enters the host cell naked, leaving the capsid outside the cell. Plant and animal viruses can enter through endocytosis, in which the cell membrane surrounds and engulfs the entire virus.

What can RNA phages teach us about viruses?

RNA phages have become model viruses for the development of a large number of novel scientific techniques. These are remarkably varied and include the controlled release of these phages into the wider environment as markers for the passage of viruses and of the ability of water treatment systems to remove viral particulates from drinking water.

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What are bacteriophages (phages)?

Bacteriophages, also known as phages, are viruses that infect and replicate only in bacterial cells. They are ubiquitous in the environment and are recognized as the most abundant biological agent on earth. They are extremely diverse in size, morphology, and genomic organization .

Is Acinetobacter RNA phage PP7 similar to coliphages?

Lately, an Acinetobacter RNA phage was identified. As judged by several criteria, these phages must be very similar to the coliphages. They have the same morphology, diameter, and molecular weight range. Sequence comparison shows PP7 to be a member of supergroup A.

How many types of RNA bacteriophages are there?

Two kinds of RNA bacteriophages are known. The Leviviridae contain a plus-sense single-stranded RNA genome within a small (∼28 nm) icosahedral protein shell. Among the simplest of known viruses, the structures of their virions, the sequences of their genomes, and the molecular details of their infection cycles have been extensively characterized.