Which is the most potent statin?
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Which is the most potent statin?
Rosuvastatin is considered as the most potent and efficient statin in managing dyslipidaemia. Although atorvastatin has a significant effect on non-HDL-C profile, its effect on HDL-C is the lowest compared to all other statins.
What is the best statin medication?
If you need high-intensity statin therapy, your doctor is likely to prescribe atorvastatin (Lipitor) or rosuvastatin (Crestor).
Which is more potent atorvastatin or simvastatin?
Dose for dose, atorvastatin is more potent than simvastatin at blocking the target enzyme, HMGCoA; this effect is overcome by using a higher dose of simvastatin. In controlled dosing studies, simvastatin 40 mg and atorvastatin 10 mg and 20 mg are equally effective.
What is the best statin with the least side effects?
In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.
Which statin is best for your liver?
Statin therapy like atorvastatin (Lipitor), (rosuvastatin) Crestor or simvastatin (Zocor), have been shown to be safe in patients with NAFLD. This is important—even if your liver function tests are abnormal from fatty liver changes, you can take statins, and the medications can often improve fatty liver.
Which statins lower LDL the most?
Our data indicate that atorvastatin was the most effective statin tested in lowering cholesterol in LDL, non-HDL, and RLP in the fasting and fed states, and getting patients with CHD to established goals, with fluvastatin, pravastatin, lovastatin, and simvastatin having about 33\%, 50\%, 60\%, and 85\% of the efficacy of …
What is the first drug of choice for cholesterol?
As with people who already have known CVD, when the decision is made to start medication, the first choice is usually a statin. (See ‘Statins’ below.) People with high triglyceride levels — Triglycerides, like cholesterol, are a type of lipid.
Is there a difference between Lipitor and atorvastatin?
Atorvastatin is the generic version of the brand name drug Lipitor. Both are available as an oral tablet that is taken once per day. Research has found no significant difference in clinical outcomes between the two versions of the medication.
Which is better Lipitor or atorvastatin?
Which cholesterol drug is safest?
Still, all in all, the statins are the safest and best tolerated of all cholesterol-lowering medications.
Which is the best statin to take for cholesterol?
Atorvastatin (Lipitor) and simvastatin (Zocor) belong to a class of medications known as statins, which are considered to be first-choice medications for treating high cholesterol. This means that both atorvastatin and simvastatin are effective for high cholesterol and work similarly.