Why is nimesulide banned in USA?

Numerous studies have established the life threatening hepatotoxic effects of nimesulide. Nimesulide is not used in the United States, and many European countries have also banned the drug because of its unacceptable rate of serious adverse reactions.

Can I buy nimesulide in USA?

Nimesulide is not available in the United States, however is used in other countries for acute pain. It may be used for pain, including period pains. Nimesulide is not recommended long-term, as for chronic conditions such as arthritis.

Is nimesulide and paracetamol tablet banned?

The government has banned the paediatric use of the common fever and pain drug nimesulide for its adverse effects on the liver, in a much- delayed move. The decision was taken by the Union health ministry after experts on the Drug Technical Advisory Board recommended banning the drug along with five others.

Is paracetamol and nimesulide same?

Nimesulide was as effective as paracetamol in reducing fever, local pain, and general discomfort. Nimesulide therefore appears to be at least as effective as paracetamol in terms of antipyretic and anti-inflammatory activity in children with inflammation of the upper respiratory tract and fever.

Is nimesulide stronger than ibuprofen?

However, the results suggest that the analgesic effect of nimesulide had a faster onset (<15 minutes) and was stronger (based on patient opinion) than that of ibuprofen. Both study drugs were well tolerated.

Is nimesulide safe for adults?

Current indications vary by country, but are generally limited to mild-to-moderate acute pain for which the recommended dose in adults is 100 mg twice daily for no more than 15 days. Chronic therapy is not generally recommended, and nimesulide is considered contraindicated in children.

What is a substitute for nimesulide?

Conclusion: Benzydamine is a well tolerated drug in patients with nimesulide- induced urticaria and it may represent a valid alternative NSAID in nimesulide- sensitive patients. Key words: benzydamine; nimesulide; adverse reactions; urticaria.

Who should not take nimesulide?

The oral form of nimesulide is not recommended for use in children below 12 years of age as the safety and efficacy data is not available. Nimesulide injection is not recommended to be used in children below 18 years of age.

What is the difference between diclofenac and nimesulide?

Results of this study suggest that nimesulide is as effective as diclofenac in the long-term treatment of osteoarthritis; however, nimesulide demonstrated a slightly superior gastric safety profile. This finding may be particularly beneficial to the elderly, who are most at risk for these side effects.

What are the side effects of nimesulide?

Nimesulide is generally well tolerated, but side effects can include headache, dizziness, somnolence, gastrointestinal upset, nausea, abdominal discomfort, diarrhea, peripheral edema and hypersensitivity reactions.

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