How is Lemierre syndrome treated?

The mainstay of treatment for Lemierre syndrome is early administration of intravenous antibiotics and surgical drainage of collections. Prolonged therapy for three to six weeks is recommended to allow time for antibiotics to penetrate into the fibrin clot and necrotic abscesses.

Is Lemierre syndrome rare?

Physicians should be aware of a rare but potentially lethal complication of oropharyngeal infections: Lemierre syndrome, which is characterized by superinfection with Fusobacterium necrophorum, jugular vein thrombosis, and septic pulmonary emboli. Its incidence has been estimated at 1 per million per year.

How do you catch Lemierre’s disease?

Lemierre syndrome most often results from a complication of a bacterial throat infection, but it has also been reported to result from infections involving other areas of the head and neck, including the ears, salivary glands (parotitis), sinuses, and teeth.

Is Lemierre’s syndrome genetic?

Background. Lemierre’s syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction.

What antibiotics are required for Lemierre’s syndrome?

Antibiotics are the cornerstone of treatment for Lemierre Syndrome. Prompt treatment should be initiated as soon as Lemierre Syndrome is suspected. Typical empiric antibiotics include a penicillin with a beta-lactamase inhibitor,clindamycin, or metronidazole.

What is Lemierre’s?

Lemierre’s syndrome is a severe illness caused by the anaerobic bacterium, Fusobacterium necrophorum which typically occurs in healthy teenagers and young adults. The infection originates in the throat and spreads via a septic thrombophlebitis of the tonsillar vein and internal jugular vein.

How long does it take to recover from Lemierre’s syndrome?

People who seek immediate medical attention for Lemierre’s syndrome have a high survival rate. Relief from symptoms may begin after several days of antibiotics. Full recovery can be expected in 3 to 6 weeks.

How common is Lemierre’s syndrome?

While not uncommon in the preantibiotic era, Lemierre’s syndrome is now a rare condition with an incidence of 3.6 cases per 1 million per year [8]. Several authors have noted an increase in the number of cases of Lemierre’s syndrome since the late 1990s [6-8].

What is the treatment for Lemierre’s syndrome?

Treatment involves prolonged antibiotic therapy occasionally combined with anticoagulation. We review the literature and a case of a child with Lemierre’s syndrome. Keywords: Lemierre, Lemierre’s syndrome, Lemierre’s disease, Lemierre syndrome, Fusobacterium necrophorum, Fusobacterium, Septic thrombophlebitis

What is ledlemierre’s syndrome?

Lemierre’s syndrome is a condition characterized by thrombophlebitis of the internal jugular vein and bacteremia caused by primarily anaerobic organisms, following a recent oropharyngeal infection. This has been an uncommon illness in the era of antibiotic therapy, though it has been reported with increasing frequency in the past 15 years.

Is Lemierre’s syndrome an anaerobic disease?

This article has been cited byother articles in PMC. Abstract Lemierre’s syndrome is a condition characterized by thrombophlebitis of the internal jugular vein and bacteremia caused by primarily anaerobic organisms, following a recent oropharyngeal infection.

What is the prevalence of Lemierre syndrome in the US?

In all major case series and reviews, Lemierre’s syndrome is primarily an affliction of previously healthy children, adolescents and young adults [2,8-17]. In a review of 114 patients, Karkos et al. [17] found that most cases presented in the 2nd decade of life (51\%), followed by the 3rd decade (20\%) and then the 1st decade (8\%).