Q&A

What is the most important gene?

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What is the most important gene?

Research into human cancer also brought scientists to TNF, the runner-up to TP53 as the most-referenced human gene of all time, with more than 5,300 citations in the NLM data (see ‘Top genes’). It encodes a protein — tumour necrosis factor — named in 1975 because of its ability to kill cancer cells.

What is the significance of the FOXP2 gene found in humans?

The FOXP2 gene provides instructions for making a protein called forkhead box P2. This protein is a transcription factor, which means that it controls the activity of other genes.

Why is the FOXP2 gene important for language and speech?

As its name suggests, FOXP2-related speech and language disorder is caused by changes involving the FOXP2 gene. This gene provides instructions for making a protein called forkhead box P2, which appears to be essential for the normal development of speech and language.

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What is Fox P gene?

Forkhead box protein P2 (FOXP2) is a protein that, in humans, is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by binding to DNA. It is expressed in the brain, heart, lungs and digestive system.

What is the best human gene?

Kerpedjiev discovered that the top gene on the list—Tumor protein p53 (TP53)—was mentioned in about 8,500 articles to date, and that it is typically included in about two PubMed papers per day….According Kerpedjiev, the top-10 most-studied genes are:

  • TP53;
  • TNF;
  • EGFR;
  • VEGFA;
  • APOE;
  • IL6;
  • TGFBI;
  • MTHFR;

What genes are unique to humans?

One such unique human gene is HYDIN2. It first appeared around 3.1 million years ago, as a duplicate of an existing gene called HYDIN. During the duplication process, “the head got chopped off and the tail got chopped off,” explains Max Dougherty from the University of Washington.

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When did the FOXP2 gene mutation in humans?

Two tiny changes in the sequence of one gene could have helped install the mechanisms of speech and language in humans. In 2001, a gene called FOXP2 was found to underlie a rare inherited speech and language disorder1.

Did Neanderthals have the FOXP2 gene?

Take FOXP2, a gene involved in language in humans. Neanderthals have FOXP2 as well, but natural selection appears to have eradicated their version from the human gene pool.

What gene makes humans talk?

FOXP2
Researchers have found a gene that could explain why we developed language and speech while our closest living relatives, the chimps, did not. The gene called FOXP2 is a transcription factor, meaning it regulates other genes.

What is the criminal gene?

Crime genes The two genes associated with violent repeat offenders were the MAOA gene and a variant of cadherin 13 (CDH13) The MAOA gene codes for the enzyme monoamine oxidase A, which is important for controlling the amount of dopamine and serotonin in the brain.

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What genes are important?

Genes (say: jeenz) play an important role in determining physical traits — how we look —and lots of other stuff about us. They carry information that makes you who you are and what you look like: curly or straight hair, long or short legs, even how you might smile or laugh.